Publications
Antibody Characterization
Epitope mapping and key amino acid identification of anti-CD22 immunotoxin CAT-8015 using hybrid beta-lactamase display.
(D.Bannister, B.Popovic, S.Sridharan, F.Giannotta, P.Filee, N.Yilmaz and R.Minter)
Use of bifunctional hybrid β-lactamases for epitope mapping and immunoassay development.
(Andy Chevigné, Nursel Yilmaz, Gilles Gaspard, Fabrizio Giannotta, Jean Marie François, Jean Marie Frere, Moreno Galleni, Patrice Filée)
Rapid and easy development of versatile tools to study protein/ligand interactions
(M. Vandevenne, G. Gaspard, N. Yilmaz, F.Giannotta, J.M. Frere, M. Galleni and P. Filee)
Antibody Development
DNA vaccination for the priming of neutralizing antibodies against non-immunogenic STa enterotoxin from enterotoxigenic Escherichia coli.
(Nadia Ruth, Jacques Mainil, Virginie Roupie, Jean-Marie Frere, Moreno Galleni, Kris Huygen.)
Protein Expression
The Bacillus licheniformis BlaP b-lactamase as a model protein scaffold to study the insertion of protein fragments
(M. Vandevenne, P. Filee, N. Scarafone, B. Cloes, G. Gaspard, N. Yilmaz, M.Dumoulin, JM. Francois, JM. Frere, and M. Galleni)
Others
Creating hybrid proteins by insertion of exogenous peptides into permissive sites of a class A beta-lactamase
(Nadia Ruth, Birgit Quinting, Jacques Mainil, Bernard Hallet, Jean-Marie Frere, Kris Huygen and Moreno Galleni.)
Characterizationofthe cattle serum antibody responses against TEM beta-lactamaseand the nonimmunogenicEscherichia coli heat-stable enterotoxin (STaI)
(A. Zervosen, C. Saegerman, I. Antoniotti, B. Robert, N. Ruth, A. Collard, F. Schynts, M. Galleni and P. Mercuri.)