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ProGenosis - Hybrid Proteins Platform

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ProGenosis, speaker at the "European Antibody Congress 2011", Geneva - 29 Nov - 1 Dec . (11/17/2011)

ProGenosis, speaker at the "European Antibody Congress 2011", Geneva - 29 Nov - 1 Dec .

Meet us in Geneva!

Meet us at the 7th annual European Antibody Congress is the industry’s most influential antibody conference covering antibody development, antibody production and monoclonal antibodies.

See more: http://www.terrapinn.com/2011/european-antibody-congress

ProGenosis at the "4th Annual Antibody Discovery & Development Forum" - 19-20 September, 2011 - Amsterdam, The Netherlands. (08/31/2011)

ProGenosis at the "4th Annual Antibody Discovery & Development Forum" - 19-20 September, 2011 - Amsterdam, The Netherlands.

Meet us soon in Amsterdam!

This 4th annual marcus evans conference will profile case studies of cutting-edge developments regarding antibody discovery and development, to provide insight into leading technologies and techniques with a clinical perspective. Addressing key themes, this conference will allow for a focus upon achieving greater efficacy, while retaining half-life, as well as designing multi-specificity and improving affinity. This conference will also provide insights on engineering earlier structural stability for greater flexibility, reducing immunogenicity, as well as seeing increased potency through glycoengineering.

See more: http://www.marcusevans.com/marcusevans-conferences-event-details.asp?EventID=18081&SectorID=31

ProGenosis; SPEAKER at "HAH 2011 -Human Antibodies & Hybridomas 2011", 7-9 November, Cannes, France. (08/31/2011)

Meet us at HAH 2011, Cannes, France.

ProGenosis will present its innovative technology for antibody development and characterization.

The HAH 2011 scientific programme will include keynote lectures, contributed papers and poster presentations emphasising all key aspects of human antibody and hybridoma technology, applications and engineering.
The scope of the conference falls broadly into eight main session categories

· Infectious Diseases
· Autoimmunity
· Molecular Biology
· Emerging Technologies
· Clinical Applications
· Therapeutic Antibodies
· Cancer
· Anti-Infective Antibodies

HAH 2011 will be placing special emphasis on and devoting at least one day of the 2011 conference to presentations covering Therapeutic Antibodies to include:

· Preclinical Issues
· Manufacturing/Stabilization
· Clinical Issues
· Regulatory and IP Issues

See more: http://www.meetingsmanagement.com/hah_2011/

ProGenosis took part to the Belgian Economic Mission to the US - June 2011 (07/14/2011)

Belgian Economic Mission to the US with Prince Philippe

This year, ProGenosis have taken part to the Belgian Economic Mission to the US.
This Belgian mission has been shaped up to be one of the biggest, with the federal government, Prince Philippe and ministers from the three regions. It was focussed on three different sectors in three different corresponding cities:
* New York
* Washington D.C.
* Boston.

The mission has kicked off in the Big Apple with a visit to Johnson and Johnson for a presentation on the future of healthcare. While in New York, a company visit to Pfizer, along with meetings involving the financial sector, was also scheduled. The regional ministers have discussed the possibility of hosting an investor breakfast to promote US direct investment in Belgium.

From New York it’s on to Washington, D.C., where the mission has coincided with the annual Bio-International convention (BIO 2011). Belgium’s booth have been officially opened by the Prince.

In Boston, several ICT and Clean-Tech companies have been visited, along with coordinating events at both MIT and Harvard.

Press release attached herewith (La libre Belgique)

Read more: llb_26_juin_2011_31.pdf

ProGenosis; Sponsor and speaker
at the "4th Antibody Engineering and Design Summit" at BOSTON - 18-21 July (07/13/2011)

ProGenosis; Sponsor and speaker  - 
at the "4th Antibody Engineering and Design Summit" at BOSTON - 18-21 July

MEET US IN BOSTON

Building on the huge success of previous Antibody Engineering & Design meetings, this industry gathering again brings together the perfect blend of world beating speakers, innovative technology developers and expert scientists to meet, learn, network and debate how to progress the field. Distinct from any big biologics show where topics range from discovery to market, the meeting will be focussing only on the cutting-edge approaches designed to enhance therapeutic antibody potential.

See more: http://antibody-engineering.com/

MAPPING OF COMPLEX EPITOPES: new DATA! (03/16/2011)

The BHP TECHNOLOGY TO ELUCIDATE A COMPLEX EPITOPE ON THE EXTRACELLULAR DOMAIN OF CD22.

Analysis of structure-activity relationships in protein interactions is a critical component of R&D programs, with potential benefits for product developments and enhanced IP. Fine description or understanding of structure-activity relationships however are extremely difficult to attain for interactions involving large molecules, as for instance in the one involving therapeutic monoclonal antibodies with membrane receptors, where critical epitopes are often not well characterized. In a recent PEDS publication, (In PEDS , 1-10, 2010), the hybrid β-lactamase display methodology, developed by ProGenosis and named BHP technology, was used to elucidate a complex epitope on the extracellular domains of CD22, a specific marker on the surface of malignant B cells, in its interaction with an antibody. The study showed that the interaction involves at least 3 discontinuous regions of the CD22 polypeptide and confirms the suitability of the β-lactamase display methodology (BHP technology) for rapid characterization of antibody epitopes.

ABOUT PROGENOSIS
ProGenosis develops and applies patented technologies for the production of bi-functional hybrid proteins (BHP) that improve antibody development and characterization. Customized services in R&D to Life Science companies are currently provided by proprietary technologies, which offer the benefits of generating expression libraries displaying all the potential epitopes of an antigen; linear and conformational as well. ProGenosis β-lactamase display technology also enhances access to protein domains known to be insoluble, difficult to express or both, including cryptic epitopes when these are not accessible in the native antigen.
Please contact N Ruth at nruth@progenosis.com for more information on services offered by ProGenosis for your R&D programs and other customized requirements.

Read more: epitope_mapping_on_cd22_using_bhp_technology_29.pdf
See more: http://progenosis.com/collaborations.php

ProGenosis now APPROVED BY by the French Ministry of Higher Education & Research. (09/20/2010)

ProGenosis now APPROVED BY by the French Ministry of Higher Education & Research.

CIR agreement.

ProGenosis is now approved by the French Ministry of Higher Education & Research (MESR) as an organisation carrying out R&D activities for private companies!

Read more: liste-organismes-agrees-pays_133865_147385_27.pdf
See more: http://www.enseignementsup-recherche.gouv.fr/cid23182/cir-liste-des-organismes-experts-bureaux-de-style-et-stylistes-agrees.html

U.S. PATENT GRANTED for the ProGenosis' technology! (08/26/2010)

U.S. patent.

ProGenosis is particularly glad to announce that it has been granted U.S. patent covering the BHP technology.

ProGenosis at the BioPartnering Europe - London, 10-12 October 2010. (08/26/2010)

ProGenosis at the BioPartnering Europe - London, 10-12 October 2010.

Meet us in London !

Meet us at the BioPartnering Europe in London next October.

BioPartnering Europe™ (BPE) 2010 is shaping up to be the powerhouse business development meeting of the year. The people who are transforming pharma business today will be there and will be discussing strategies that you can’t afford to miss!

See more: http://www.techvision.com/bpe/

New paper: Protein purification and On-Column Refolding (05/03/2010)

Protein purification and On-Column Refolding

Purification and On-Column Refolding of Polyhistidine-tagged Staphylococcus aureus alpha-hemolysin (His-alphaHA) Inclusion Body on the ProfiniaTM Protein Purification System.

Read more: technote_biorad_v2_24.pdf

Sponsor of the "3rd Annual Antibody Discovery and Development Forum"; 17-18 June 2010. (04/09/2010)

17-18 June 2010 in Amsterdam

ProGenosis, business sponsor of the "3rd Annual Antibody Discovery and Development Forum", will present its proprietary technology platform allowing fine epitope mapping and efficient antigen development.

See more: http://www.marcusevans.com/marcusevans-conferences-event-details.asp?EventID=16602&SectorID=31

ProGenosis: Sponsor of the "Antibody Engineering & Design" - Frankfurt - February 24th & 25th 2010. (01/05/2010)

ProGenosis: Sponsor of the "Antibody Engineering & Design" - Frankfurt - February 24th & 25th 2010.

February 24th & 25th 2010, Marriot Courtyard

Progenosis will present on day 2 the BHP technolgy for epitope mapping.
"The Bifunctional Hybrid Protein (BHP): a new enabling technology for non-linear epitope mapping"
*Identification of epitope region and key amino-acid determination using BHP technology as a BioTool.
*Enabling a unique and original epitope display

By Dr Fabrizio Giannotta, Chief Executive Officer, ProGenosis S.A

See more: http://www.hansonwade.com/events/antibody-engineering-and-design/day-two.shtml

ProGenosis at the BIOCONNEXION day « DIAGNOSTICS »! (12/06/2009)

in Montpellier (France) on December 08, 2009.

For new opportunities in medical diagnostics development, meet us at the « BIOCONNEXION DIAGNOSTICS » day in Montpellier (France) on December 08, 2009.

Our technology enables the three-dimensional reconstruction of domains and sub-domains of an antigen target.
The use of such reconstructed domains or sub-domains for immunisation purposes, rather than using the whole antigen, allows to focus the immune response against a preselected region of this antigen. The raising of antibodies directed against non-immunodominant or cryptic regions is made easier.

Customized antigen development provides a wide range of applications such as therapeutic antibodies or vaccines development. These de novo antigens can also be used as reagents in In Vitro Diagnostics or as biotools for the detection of receptor-ligand interactions.

A NEW PROTEIN PRODUCTION PLATFORM (09/23/2009)

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ProGenosis at the BIO International Convention. (05/10/2009)

ProGenosis at the BIO International Convention.

May 19-21 2010, Atlanta, Georgia.

The participation of ProGenosis goes around 2 main points:

1 - A booth in the Belgium Pavilion where you will have the opportunity to meet us and discover our technology,
2 - Participation at the BIO Business Forum.

Meet ProGenosis at Berlin in May! (05/05/2009)

2nd Annual Antibody Discovery and Development Forum, 14-15 May, Berlin

Addressing and Overcoming the Key Challenges in Preclinical and Clinical Development - Hear how technological innovation in early discovery has impacted later-stage development and how this technology can be exploited most effectively for the next generation of antibody therapeutics.

ProGenosis at the "BIO-Europe Spring 2009" in Milan ! (12/30/2008)

ProGenosis at the "BIO-Europe Spring 2009" in Milan !

MARCH 16-18, 2009 - MILAN, Italy

ProGenosis will present an innovative technology for :
- Epitope mapping
- Antibody development
- Protein expression

Read more: lefleat_1pg_final_laser_14.pdf
See more: http://www.ebdgroup.com/bes/

Meet ProGenosis at BIOContact Québec 2008. (09/15/2008)

October 1-3, 2008

ProGenosis will present the BHP technology on the 2nd of October at 16:30 , Salon Bellevue.

See more: http://www.biocontact.qc.ca/english/default.html

Meet ProGenosis at the "European Antibody Congress" in Geneva. (07/07/2008)

Meet ProGenosis at the "European Antibody Congress" in Geneva.

From December 1 to 3rd, 2008 : The most influential antibody conference to take place.

ProGenosis will present its Bifunctional Hybrid Protein technology applied to antibody development and characterization.

See more: http://www.terrapinn.com/2008/antibody/conf.stm

Meet ProGenosis at BIO San Diego - 2008 (05/21/2008)

Meet ProGenosis at BIO San Diego - 2008

From June 17 to 20, 2008 ProGenosis will take part to one of the most important convention in its field of activity.

The participation of ProGenosis goes around 3 main points:

1 - a booth in the Belgium Pavilion where you will have the opportunity to meet us and discover our technology,
2 - a presence at the BIO Business Forum.
3 - a presentation of the Bifunctional Hybrid Protein technology applied to antibody development and difficult to express protein.

ProGenosis would be pleased to greet you if you attend this convention. To get the most of this encounter may we kindly ask you to fix an appointment by sending us a mail – info@progenosis.com.

See more: http://www.bio2008.org/

ProGenosis will present at Bio-Europe 2008 (04/04/2008)

ProGenosis will present at Bio-Europe 2008

From April 7 to April 9, 2008 ProGenosis will take part to one of the most important convention in its field of activity.

ProGenosis will be presenting its Bifunctional Hybrid Protein technology applied to antibody development and difficult to express protein.
Comes to learn more about us to the "Next Generation Presentations" session.

See more: http://www.ebdgroup.com/bes/index.htm

Meet ProGenosis at PEGS – 2008 (04/04/2008)

The essential protein engineering summit.

From April 28 to May 2, 2008 ProGenosis will take part to one of the most important convention in its field of activity.

The participation of ProGenosis goes around 2 main points with a poster presentation:

1 - Monoclonal Antibody
2 - Difficult to Express Proteins

ProGenosis would be pleased to greet you if you attend this convention. To get the most of this encounter may we kindly ask you to fix an appointment by sending us a mail to info@progenosis.com.

See more: http://www.pegsummit.com/

Meet ProGenosis at "European Antibody Congress". (11/03/2007)

The leading event for the advancement of antibody discovery and development.

5 -7 Nov. 2007, Lyon, France.

See more: http://www.terrapinn.com/2007/antibody/

ProGenosis will present at PSF 2007 (11/03/2007)

ProGenosis will present at PSF 2007

19-20 Nov. 2007, AstraZeneca, Cheshire, UK.

ProGenosis will be presenting "The Bifunctional Hybrid Protein, a new versatile BioTool for recombinant protein expression and downstream R&D activities" at this event.
Download the presentation here under.

Read more: psf2007_progenosis_7.pdf
See more: http://www.astrazeneca.se/16089_19089.aspx?mid=0

ProGenosis has moved to new facilities. (11/03/2007)

ProGenosis has moved to new facilities.

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ProGenosis has moved to new facilities located into the genomics and proteomics center (CBIG/GIGA) inside the university hospital. This new facilities allows ProGenosis to better meet the need of customers and to attend its development strategy.
The equipment of the BHP technology platform has been established with the collaboration of ANALIS' Product Specialists.

See more: http://www.giga.ulg.ac.be/extranet/project.htm

Enhance your chance to get soluble protein domains. (08/06/2007)

Enhance your chance to get soluble protein domains.

ProGenosis has launched a brand new service for difficult to express proteins.

BHP technology uses a very robust and efficient positive drug-based screening system, which enables the easy and straightforward selection of fully soluble and well-folded proteins.

Click to the link below to learn more about this service or download the pdf file.

Read more: bhp_exp_rprot_5.pdf
See more: http://www.progenosis.com/services.php?subservice=4

Meet ProGenosis at BIO Boston – 2007 (04/23/2007)

Meet ProGenosis at BIO Boston – 2007

From May 6 to May 9, 2007 ProGenosis will take part to one of the most important convention in its field of activity.

The participation of ProGenosis goes around 2 main points:

1 - a booth in the Belgium Pavilion where you will have the opportunity to meet us and discover our technology,
2 - a presence at the BIO Business Forum.

ProGenosis would be pleased to greet you if you attend this convention. To get the most of this encounter may we kindly ask you to fix an appointment by sending us a mail – info@progenosis.com.

See more: http://www.bio2007.org/

ProGenosis, industrial associated partner of Nano2Life (04/23/2007)

ProGenosis, industrial associated partner of Nano2Life

ProGenosis is the company of the month of the first Nanobiotechnology network.

ProGenosis has been selected as company of the month (April) by the selection committee of Nano2Life. As industrial associated partner, ProGenosis will act with public & non profit organizations to sustain the mission of the network.
Nano2Life is the first European Network of Excellence in nanobiotech supported by the 6th Framework Programme of the EU. Its aim is to merge existing European expertise in the field of nanobiotechnology.

See more: http://www.nano2life.org/